Some medical conditions influence whether methylcobalamin or cyanocobalamin is the more appropriate form
All of this was explained to me when I met two representatives of the MHRA two years ago, (their offices, incidentally are a nightmare for vertigo sufferers like me its all wall to wall glass even the floors)
The consensus in the scientific community supports B12s high safety profile, even at elevated levels, with no documented risk of toxicity in healthy individuals
Vitamin b12 needs those enzymes and intrinsic factor to get absorbed in gut
Not appropriate for those with B12 hypersensitivity
In a trial of patients with T2DM and BMI 27 kg/m2 or more receiving semaglutide injection for weight management, retinal disorders were reported by 6.9% of patients treated with semaglutide 2.4 mg/week, 6.2% of patients treated with semaglutide 1 mg/week, and 4.2% of patients treated with placebo