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Elevated levels of ferritin and transferrin, markers of iron dysregulation, have been observed in clinical ARDS cases, linking iron metabolism to disease severity ( Mitochondrial dysfunction exacerbates iron-driven ferroptosis by impairing the organelles ability to sequester and regulate iron levels

Irradiation induced ultrastructural changes of the intestinal TJs

They also play a major role in managing blood pressure and balancing electrolytes like potassium and sodium

64604-19-9 Pinealon Mol

Bruscolini, A

Beyond physical attachment, adhesion activates host signaling pathways upregulates tight-junction proteins and induce antimicrobial peptide secretion, strengthening the barrier and limiting pathogen invasion (Wang et al., 2025)