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doi: 10.1038/oby.2003.78 38 BourgeoisBF

This was compared to a 3.1% weight loss in those taking a placebo

In in vivo and in vitro studies, melatonin was proven to increase the level of Nrf2 in cardiomyocytes exposed to oxidative stress

The other is an indirect interaction through the release of metabolites, including SCFAs, which can influence physiological responses through different signaling pathways (58)