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Researchers suggest there is a chance it may boost the expression of the early growth response 1 gene, which may play a role in producing cytokines and growth stimuli, and possibly aid in the initial assembly of the extracellular framework, inclusive of collagen

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These nerve fibers release neuropeptides that trigger the production of inflammatory mediators such as cytokines, and prostaglandins, which activate nociceptive pathways (174)