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Multiple compounds that were thought to be antagonists at D 2 -like receptors (including the antipsychotic drugs haloperidol, chlorpromazine, and clozapine) have been demonstrated to possess inverse agonist activity at D 2 and D 3 receptors

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PMID: 10468881

The compounds improve hepatic and visceral fat clearance preferentially because those stores have higher metabolic turnover, but subcutaneous fat loss follows general body composition patterns determined by genetics, not injection site

Metformin enhanced the effect of pirfenidone on pulmonary fibrosis in mice

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