The HMG-CoA reductase inhibitor, simvastatin, exhibits anti-metastatic and anti-tumourigenic effects in ovarian cancer
Next, we will summarize some promising medicine monomers that activate the GSH system based on the categories of natural medicines, including flavonoids, terpenoids, phenolic acids, quinones, and alkaloids (Table 2, Supplementary Table S2)
Kalt, M
Recent studies have demonstrated that in triple-negative breast cancer (TNBC), a substantial decrease in cancer cell GSH levels and a significant increase in cellular superoxide levels can be induced by the administration of a dual metabolic inhibitor of GLS and xCT (SLC7A11), which promotes apoptosis [46]
Faecal microbiota transplantation protects against radiation-induced toxicity
The study indicated that low levels of glutathione caused an increase in psoriasis inflammation