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However, more recent studies and meta-analyses with larger sample sizes suggest the opposite

The SWITCH-SEMA studies were significant in understanding the benefits of switching to SMG, particularly in terms of the efficacy, safety, and tolerability of SMG compared to the previous medication

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A 2017 meta-analysis included five randomized clinical trials in a total of 631 adults with insulin resistance who took 2 or 3 g/day L-carnitine or placebo for 4 weeks to 12 months