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Clinical trials have shown that L-Carnitine supplementation may improve cardiac function and reduce symptoms in patients with heart failure.

The first formal human safety test appeared in early 2025: two healthy adults given intravenous infusions, no control group, measuring only whether their organ markers moved

Renzoni E, Abraham DJ, Howat S, Shi-Wen X, Sestini P, Bou-Gharios G, Wells AU, Veeraraghavan S, Nicholson AG, Denton CP, Leask A, Pearson JD, Black CM, Welsh KI, du Bois RM: Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts

Hattori K, Ishikawa H, Sakauchi C, Takayanagi S, Naguro I, Ichijo H

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Case report: A Chinese patient with glutathione synthetase deficiency and a novel glutathione synthase mutation