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10.1016/j.stem.2008.07.004 Cell Stem Cell 126 MolinaL.BustamanteF.OrtloffA.RamosI.EhrenfeldP.FigueroaC

For people with raised NF-B levels, the nuclear factor NF-kappa-B (NF-B) transcription factor family is a therapeutic target since it plays a role in several inflammation-driven chronic disorders

Cells drop into senescence in increasing amounts as we age, and its one of the leading theories on why humans grow old and die eventually, the number of cells that are dividing and renewing the body drop in proportion to the number of cells in senescence, leading to higher and higher numbers of dysfunctional cells (that can cause cancer or inflammation), and the human body degrades until it can no longer function and we die

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