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The highest score of 10 points reflects the greatest impairment, while the lowest score of 0 points represents normal forelimb function

Efficacy is slightly reduced in those with diabetes, but participants were still able to lose 16.9% of body weight alongside a 2.16% reduction in HbA1c from baseline after 36 weeks [118]

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[14] If biotin is being used for general hair or nail support in a non-deficient person, changes (if any) would also take several weeks or months, and its possible no significant improvement will occur in those who already have sufficient biotin

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PLoS ONE 10 , e0126177 (2015)