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During productive adenovirus infection, the late region 4 (L4) 100-kDa protein (100 K), the first viral late protein, selectively inhibits host cellular protein synthesis and induces the translation of viral late mRNAs to initiate the late phase of viral infection [138]

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Wisit Cheungpasitporn, Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, USA