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It is always different and the type of materials/product you receive is never fully the same
10.1038/s41372-019-0367-0 265
Egawa K, Kitagawa K, Inoue K, Takayama M, Takayama C, Saitoh S, et al
Regulation of cortical structure by the ezrin-radixin-moesin protein family
Its important to remember that these therapies work best as part of a comprehensive wellness plan including proper diet, exercise, sleep, and other hormone or nutrient optimizations as needed
Beyond the safety question, a rinse-off soap also can't stay on skin long enough to meaningfully affect melanin so even a "safe" version wouldn't do much regardless
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