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Ligand binding and subsequent phosphorylation of IGF-1R triggers the activation of two major signaling cascades via the insulin receptor substrate 1 (IRS-1): the phosphatidylinositol 3-kinase/AKT kinase (PI3K/AKT) pathway and the RAF kinase/mitogen activated protein kinase (RAF/MAPK) pathway which stimulate proliferation and protection from apoptosis [11]

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Effects of L-carnitine on the mRNA expression levels of Star, Cyp11a1, and Hsd17b3 genes According to Fig

Effect of melatonin on mammary carcinogenesis in intact and pi-nealectomized rats in varying photoperiods

In summary, the increase in erythrocytes in HAPC rats was associated with enhanced hematopoietic function in the bone marrow and reduced erythrocyte apoptosis

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