The Influence and Mechanism of GLP-1 RAs in Modulating Hypertension Hypertension, a chronic cardiovascular disease, affects a large number of individuals, with its prevalence increasing, making it a major cause of mortality and disability [72]
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Alexander Kokkinos Carel Le Roux To view or add a comment, sign in Tirzepatide: Redefining Outcomes in Diabetes & Obesity Care Clinical trials show tirzepatide, a dual GIP/GLP-1 receptor agonist, is delivering results beyond expectations: Up to 20.9% mean weight loss at 72 weeks (SURMOUNT-1, NEJM) 94% risk reduction in progression from prediabetes to type 2 diabetes over 3 years Superior HbA1c reduction and weight control vs leading GLP-1 therapies (SURPASS program) With manageable side effects and durable outcomes, tirzepatide is reshaping how we approach metabolic disease
10.1016/j.taap.2018.04.018 16 CornetM
and also of oxidative stress 7,19,20