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GH accelerates oncogenic signaling for common oncogenic processes and tumor development, including proliferation, migration, invasion (Mukhina et al., 2004), and prevents apoptosis by exerting autocrine or paracrine effects on cancer cell behavior and neighboring cells within the tumor microenvironments (Perry et al., 2017)

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For a 250 g/ml solution and a research subject weighing 70kg, targeting a 10 g/kg dose: 10 g/kg 70kg = 700 g total dose 700 g 250 g/ml = 2.8ml injection volume For repeat-dose protocols, researchers often split daily doses into twice-daily administrations (e.g., 5 g/kg every 12 hours rather than 10 g/kg once daily), which maintains more stable plasma concentrations

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