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This phenomenon, known as reperfusion injury, involves the oxidation of cellular components, mitochondrial dysfunction, and the activation of inflammatory pathways [91, 92]

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., Dubbeld, M.A., Narum, D.L., van de Rijke, F.M., van Gemert, G-J., van der Linde, X., Bannister, L.H., Janse, C., Waters, A.P., and Thomas, A.W

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Firstly, CD206 was employed as the M2 macrophage marker to confirm macrophage polarization status using immunofluorescence staining performed under inflammatory stimuli (LPS and IFN-)