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Although I do not routinely measure longitudinal change in body composition or bone mass in people taking GLP-1s, mostly because of the cost of DXA scans, significant muscle or bone loss are two objective manifestations of excessive weight loss that should lead to stopping or slowing treatment

Neuron 101 , 1099-1108 e1096

Patients who miss doses should follow the prescribing guidance provided with treatment and discuss prolonged interruptions with their clinician before restarting