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While mutagenesis studies clearly reveal that these residues within TM2 and ECL2 are important for both GLP-1 and oxyntomodulin function, alanine mutations in these regions generally had a larger impact on GLP-1 (Figs

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Author contributions FO: Funding acquisition, Resources, Writing review & editing, Writing original draft, Software, Visualization, Methodology, Project administration, Validation, Conceptualization, Investigation, Supervision