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Adipogenesis involves multiple steps, including the activation of specific adipogenic transcription factors, including peroxisome PPAR-, CCAAT/enhancer-binding proteins (C/EBPs), and sterol regulatory element binding protein (SREBP), which shape the mRNA/protein networks driving adipocyte development [43,44,45]

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Side effects, long-term tolerability and whether patients ultimately choose to remain on the implant are among the questions doctors say future clinical trials will need to answer

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