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264,265 In AD, lysosomal acidification deficits may weaken the clearance of A, ultimately leading to the accumulation of extracellular A plaques

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10.1039/an9618600748 56 NjusD.KelleyP

The salutary effects of GLP-1RA on endothelial function could also be exploited for ED amelioration 96 , as the GLP-1 receptor was detected in endothelial cells and GLP-1RA were found to affect endothelial function by stimulating nitric oxide production 99

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As biological matrix can metabolize spiked pure compound we added each NAD form individually at different stages of the extraction (Supplementary Table 1) and followed recovery in enzymatic assays