In one study, microdosing GLP-1s supported moderate weight loss of up to 10 pounds over 40 weeks in participants. MICRODOSING GLP-1 BENEFITS Do More, Age Less Modulated inflammatory pathways in clinical trials. Studies found a reduced risk of cognitive decline Supported cardiovascular health in clinical trials Improved mitochondrial function and oxidative stress in clinical trials Low doses reduced side effects in clinical trials Supported moderate weight loss of up to 10 pounds over 40 weeks in one study *See studies cited below
There is also a bigger ongoing study with over 2,000 people to confirm these results and gather more information, which will continue for about 89 weeks
The right response depends on whether the episode followed a meal, began after a GLP-1 dose increase, occurs with diarrhea after travel, or is accompanied by pain, vomiting, bleeding, fever, or weight loss
At minimum: IGF-1 every 4 weeks, fasting glucose and insulin every 2 weeks initially (monthly once stable), HbA1c every 6 weeks, liver enzymes monthly, and comprehensive metabolic panel quarterly
doi: 10.1038/S41598-019-55524-W 116 O'NeilPMBirkenfeldALMcGowanBMosenzonOPedersenSDWhartonSet al
Its potential in metabolic research is formidable, making it a compound of immense interest
