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If retatrutide reduces major cardiovascular events (like semaglutide did in SELECT), the heart rate increase will be viewed as a pharmacologically interesting but clinically irrelevant side effect
Radiat Res 155:536542
It is used for these properties mentioned above to treat diseases such as diabetes and obesity, among other diseases
BPC-157 is studied for its role in: Tendon, ligament, and soft tissue repair - investigated for its effects on fibroblast migration, collagen deposition, and connective tissue remodelling
These diverse therapeutic effects of semaglutide raise a vital mechanistic question, namely whether these effects align along a single axis, or whether the drug provides separable cardiovascular benefits that are independent of the magnitude of weight reduction achieved
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