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74 However, RCTs are still needed to investigate the effects of GLP-1 RAs on HF outcomes, mortality and clinical outcomes in both HFpEF and HFrEF

For example, Lemme GLP-1 Dailys website states that the product can promote your bodys GLP-1 production, reduce hunger and cravings, and support fat reduction with three clinically studied ingredients. However, their website points to studies in which the ingredients were investigated separately, in less than 200 participants

An increased number of available drugs in this class could drive prices down due to competition

Lastly, semaglutide GLP-1 has been shown to help to reduce body weight and blood pressure, which is important for those with type 2 diabetes are may be overweight or obese

Statements Author contributions Q-XL and J-DX wrote the manuscript

van Bloemendaal, L., Ten Kulve, J