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On one hand, its good [for sales] because it creates a lot of turnover

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Koeth RA, Wang Z, Levison BS, Buffa JA, Org E, Sheehy BT, Britt EB, Fu X, Wu Y, Li L, Smith JD, DiDonato JA, Chen J, Li H, Wu GD, Lewis JD, Warrier M, Brown JM, Krauss RM, Tang WH, Bushman FD, Lusis AJ, Hazen SL

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Kadowaki T, Yamauchi T

Alternative interpretations include (a) trial design (active comparator narrows the margin to detect superiority) and (b) underlying biology that limits incremental benefit on plaque stabilization beyond a threshold