People who are already relatively lean (under 25% body fat for men or under 32% for women) may find that GLP-1 medications produce less dramatic weight loss but still improve body composition through targeted fat reduction
Oral Wegovy launched in the US on January 5th
Due to the expression of GLP-1 receptors in testicular cells, they can raise testosterone levels and increase sperm motility and metabolism (101)
SGLT-2 inhibitor therapy added to GLP-1 agonist therapy in the management of T2DM
The appetite-suppressing effects of these medications, coupled with their ability to slow gastric emptying and induce a prolonged feeling of fullness, contribute to reduced food intake and subsequent weight reduction
However, until the company accumulates a meaningful body of independent patient reviews, we advise prospective patients to ask detailed questions about pharmacy sourcing, cancellation terms, and provider credentials before committing