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Managing gastrointestinal side-effects and preventing treatment discontinuation with GLP-1 therapies GI symptoms are the most common adverse effects of GLP-1 therapies, with nausea, constipation, diarrhea, and vomiting occurring in around 40 % of patients [11,[30], [31], [32]]

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In contrast, we demonstrate that a single dose of 3 mg/kg psilocybin does not influence the body weight or food intake of ob/ob mice on a high-fat diet (Fig