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However, tachyphylaxis (tolerance) develops rapidly within 3-5 days of continuous dosing, food intake returns to baseline levels (Cote et al., 2010)

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The paper topics, layout, writing, editing, and final approval was done by both authors

Select therapeutic modalities, such as laser treatments and topical agents, may have some effectiveness for some pigmentation conditions

Your clinician will review your prior prescription and treatment history to determine whether continuing at a higher dose is medically appropriate

Some patients use DSIP for specific periods of sleep disruption (travel, high-stress periods, training cycles requiring optimal recovery) with targeted short-term protocols, while others implement ongoing protocols with periodic cycling for sustained sleep optimization