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The aromatic ring of GRL0617 fits into the S3 subsite, while the naphthalene group fills the S4 subsite
doi:10.4103/tcmj.tcmj_255_19 [45] Agarwal A, Sengupta P, Durairajanayagam D
Circ Res 61(3):396408 Wu X, Prasad PD, Leibach FH, Ganapathy V (1998) cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family
The two compounds act on different systems pharmacologically
Similar to albumin, AAT can function as an indirect free radical scavenger by interacting with neutrophil alpha defensins, 159-161 free fatty acids, 162 and free heme
OTA affected the gut through decreasing the absorption of nutrients, disrupting the permeability of the intestinal lining, causing cell apoptosis, and modifying the immune system (Liew and Mohd-Redzwan, 2018)
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