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Compounded GLP-1 medications are prepared by licensed pharmacies and are not FDA-approved finished products

They show an intrinsic peroxidase-like activity, which could efficiently catalyze the decomposition of H 2 O 2 to produce OH radicals

Standard target: 99% purity

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Other FINs directly suppress GPX4 activity, such as ML162, DPI7, and Ras-selective lethal small molecule (RSL-)-3 (Li et al., 2020