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Examples of Tirzepatide in Guidelines Diabetes Standards of Care 2025 , American Diabetes Association 8.17: In people with diabetes and overweight or obesity, the preferred pharmacotherapy should be a glucagon-like peptide 1 receptor agonist or dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide 1 receptor agonist with greater weight loss efficacy (i.e., semaglutide or tirzepatide ), especially considering their added weight-independent benefits (e.g., glycemic and cardiometabolic). Please note: This article is current as of June 12, 2025

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