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Some preclinical comparative studies have suggested that GHK-Cu performs comparably to 5% minoxidil in stimulating hair follicle growth in organ culture, though through a different mechanism minoxidil opens potassium channels and increases blood flow, while GHK-Cu acts on growth factor signaling and matrix remodeling

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Additionally, other studies indicate that test sensitivity depends on the carrier molecule but that also the density and distribution of the AXO can have an important role 22,23,24

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The observed benefits include improved skin laxity, firmness, reduced lines, and increased skin density and thickness [15]