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[70] found in vivo and in vitro studies that GLP-1 and its analog exendin-4 were able to induce an increase in ABCA1 mRNA, increase the expression of apo AI mRNA and promoter, thereby increasing apo AI secretion, indicating that GLP-1 in hepatocytes may mediate the outflow of intracellular cholesterol to apo AI through the ABCA1 pathway

This can include: Baseline metabolic panel : To assess kidney function, liver enzymes, and electrolytes

Routine monitoring may be worthwhile for longer courses, particularly with existing liver disease

Semaglutide starts at 0.25 mg weekly

the pharmacy side working and the health system side all being able to process these prior authorizations in an efficient, effective way, said Dr Annie Moore, an internist at CU Health in Denver

doi: 10.1093/ajhp/zxaa413