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the pump runs continuously, burning ATP and forcing the cell to oxidize stored fat for fuel

Proper thyroid hormone replacement or stabilization is therefore the foundation of any weight management plan for people with thyroid disease, and additional therapies must be layered carefully on top of established thyroid treatment

doi: 10.1186/s13054-015-0913-x 151 ColleMBattinJCoquelinJPRochiccioliP

Hyperglycemia itself damages blood vessels through several mechanisms

Because it is a triple agonist that includes glucagon, it directly stimulates lipolysis and increases resting energy expenditure, resulting in significantly greater weight loss in head-to-head phase 2 trials

Type 2 diabetes remission rates increase sharply