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The theoretical basis for recomposition rests on separating energy balance from substrate utilization

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5 Still, this research shows what happens when you stop the medications suddenly without a gradual decrease in dose (a taper), and with adequate lifestyle support alongside it

273 In addition, in a rat model of inflammatory OA induced by monoiodoacetic acid (MIA), researchers have shown that the activation of GLP-1R triggers the PKA/CREB signaling pathway, leading to a reduction in cartilage inflammation

When to contact your healthcare provider: Patients should reach out to their prescriber or pharmacist if they have used medication that may have been compromised, particularly if they experience unexpected hyperglycemia, loss of appetite control, or unusual injection site reactions