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Assessed through medicinal-chemistry optimization and pathway-level translational frameworks

Women may respond slightly differently in terms of where fat loss occurs first, but the mechanisms are identical regardless of sex

The authors reported that AOD-9604 stimulated lipolysis in isolated adipocytes and that chronic daily treatment in obese Zucker rats produced reductions in body weight gain of more than 50% relative to untreated controls over the treatment period, without effects on insulin sensitivity or IGF-1 levels [3]

1 It has an estimated prevalence of roughly 6% in the UK

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