smaller trial data Dosing convenience Daily injection required Once or twice weekly (with DAC)
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References Vincent I.M., Ehmann D.E., Mills S.D., Perros M., Barrett M.P
185 In recent years, animal and in vitro studies have demonstrated the beneficial effect of KBs on the course of PD due to their function in mitochondrial homeostasis
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Pyridoxine Pyridoxine (vitamin B 6 ) metabolism in DS has been studied and was shown to improve the levels of 5-hydroxyindole, a metabolite of serotonin, as effectively as 5-hydroxytryptophan administration