Importantly, extracellular glutamate levels are tightly regulated, as their overabundance at synapses are inked to glutamate-induced excitotoxicity, a condition caused by elevated extracellular brain glutamate concentrations combined with excessive glutamatergic stimulation, resulting in surges in intracellular calcium levels and the initiation of neurotoxic signaling pathways, that are implicated in several neurological pathologies, including neurodegenerative disorders 6,8
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En renforant lefficacit des cellules immunitaires, il permet lorganisme de combattre plus efficacement les infections virales et bactriennes tout en rduisant les risques de complications
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CF patients with the null phenotype for GSTM1 (GSTM*0) have a poorer prognosis than individuals with other GSTM1 alleles [91]
