de Cabo R, Mattson MP
GLP-1 receptor agonists work by mimicking the effects of 1, 2, or 3 naturally produced digestive hormones, including glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide (GIP)
Known for its susceptibility to immune-mediated diseases and distinct immune response profile, the Lewis rat serves as a specialized model for investigating neuroinflammation and related neurodegenerative processes
Briefly, Tni insect cells were grown in ESF 921 serum-free media to a density of 3.5 million/mL and infected with GLP1R, DNGs and G1-2 baculovirus at multiplicity of infection (MOI) ratio of 3:3:1
ROS are highly reactive oxygen-derived molecules (e.g., superoxide anion O 2 , hydroxyl radical OH, hydrogen peroxide H 2 O 2 )
doi: 10.1186/s12887-019-1828-5