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Tirzepatide Tirzepatide (Mounjaro, Eli Lilly) is a dual incretin agonist that targets both GLP-1 and GIP receptors

Many people seem to experience symptoms like those you mention - where it has been mentioned in posts my memory is that the individuals concerned report the sleepiness as something that continues as they move into maintenance shots

This includes maintaining a consistent sleep schedule, creating a restful sleeping environment (cool, dark, and quiet), avoiding stimulants like caffeine and nicotine close to bedtime, and limiting exposure to screens before sleep

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Gerschman R, Gilbert LD, Nye SW, Dwyer P, Fenn WO

Heart rate increased from baseline across all treatment groups, an effect consistent with prior trials of semaglutide