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On the technical side, the analytical evaluation of (poly)phenol, especially in biofluids, currently faces issues regarding reference standards

These cleavable linkers exploit the redox potential differences between the extracellular environment and the intracellular milieu, particularly the elevated levels of reducing agents such as glutathione (GSH) found within cells

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Additional documented functions include the biosynthesis of vitamins, the metabolism and deconjugation of bile salts, diverse enzymatic activities that contribute to nutrient bioavailability, and the neutralization of dietary or microbial toxins (147)