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GLP-1 (semaglutide or tirzepatide) Therapy in Older Adults: Balancing Benefit & Risk Beyond Age 65 Joshua Silva, MD Dec 12, 2025 4 min read Medically authored by Joshua Silva, MD | Evidence-Based Weight Loss at Potere Health MD Last clinically updated: December 2025 Many discussions about GLP-1 medications in older adults come from friends, family, or acquaintances , as well as online forums, news stories, and social media posts

This is the adaptation phase where the body adjusts to GLP-1 and GIP receptor activation

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[5] It is encoded by the codon AUG

10.1124/jpet.300.3.958 221 Petkova-KirovaP.RakovskaA.Della CorteL.ZaekovaG.RadomirovR.MayerA