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These modifications collectively address the major limitations of natural amylin - its tendency to aggregate into toxic fibrils, rapid degradation, and poor pharmacokinetic properties - while preserving and enhancing its beneficial metabolic effects

2 in Taiwan) (Priyadarsini et al., 2025)

Herz 20 (3), 169186

free induction decay points= 2,048, spectral width=2,000 Hz, number of averages=64)

2024;103(11):e37421

DDS innovationsthrough pharmacokinetic optimization, precision targeting, and combinatorial strategiesrepresent transformative solutions to overcome these barriers, offering safer, more effective therapeutic options for complex clinical scenarios