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NLRP3 may act as a biomarker for neuroinflammation in PD and could be used to monitor disease progression [231]

Clinical Trials Using Senolytics The enthusiasm for senescent cell clearance across diseases of aging, along with a therapeutic approach that could be translated to patients, led to the first clinical trial of senolytic therapy (D+Q) in adults with idiopathic pulmonary fibrosis (IPF)

Additionally, there was a decrease in the body mass index (BMI) and the patients reported that their menstrual cycles became more regular and that their hirsutism diminished (136)

Both show promise

This research validates the physical reality of "brain fog" and cognitive dysfunction, showing it is not a psychological symptom but a direct result of localized antioxidant depletion and cellular energy failure