The amount of weight you can lose on Semaglutide varies depending on several factors, including your starting weight, lifestyle habits, diet, exercise routine, and individual response to the medication
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This can reduce how much food a person eats during the day
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However, the results should not be interpreted as evidence that these medications prevent dementia, progressive cognitive decline, or psychiatric disease, because the study relied on diagnosis codes and remains vulnerable to residual confounding and misclassification
4 Retatrutide has none of these yet, and the realistic UK approval window is late 2027 to mid 2028, with NHS access from 2029 at the earliest