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PLoS One 19(8) Shaefer CF Jr., Kushner P, Aguilar R (2015) Users guide to mechanism of action and clinical use of GLP-1 receptor agonists

FDA Approval for Weightloss Despite being on the market since 2017, Wegovy has only been approved for chronic weight-loss management and for non-diabetic use in 2021

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The metabolic adaptability of Tregs also highlights the complexity of tumor therapy, necessitating simultaneous intervention in metabolic limitations of effector T cells (e.g., glucose competition) and alternative metabolic pathways of Tregs (e.g., lactate utilization) (100)

Ghusn and Hurtado, 2024)

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