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For the possible but so far not recognized BPC 157/NO-system connection, we indicated [171] that under the same L-NAME non-responsive/L-arginine responsive paradigm, this counteraction of resembling negative-like symptoms (cognitive dysfunction) [204,205,206,207] completely corresponded to the counteraction of the similar positive-like symptoms [200] (acute apomorphine, chronic methamphetamine, and acute MK-801 induced effects and acute haloperidol induced catalepsy) [208,209,210,211,212,213,214,215]

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Of this, 17 records were finally included in the review

Brain Res 2009

The review noted that BPC-157 interacts with the nitric oxide system, VEGFR2, and multiple growth factor pathways