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Lawrence Herman: Served on an advisory board for Novo Nordisk and is on the speakers bureau for Novo Nordisk

Thus, although GIPR in the AP is required for the weight loss effects of GIPR agonists, it is not the target of therapeutic GIPR antagonists, supporting recent findings that Gipr KO in GABAergic neurons also abolished responses to GIPR agonism but not antagonism 6

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Recently, the discovery of reversible/irreversible covalent inhibitors targeting cysteine residues in and around the ATP-binding pocket of kinases has been gaining considerable attention (94)

doi: 10.1093/cid/ciaa329

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