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Top-dose phentermine and topiramate cost-effective for adolescents after five-years owenhaskins Sep 13, 2023 3 min read Updated: Sep 14, 2023 A study led by researchers from Columbia University Irving Medical Center, who assessed the cost-effectiveness of a range of anti-obesity medications in adolescents, have concluded that top-dose phentermine and topiramate (Qsymia) as adjunct to lifestyle counselling was estimated to be cost-effective after five years

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