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Topical glutathione is widely used for pigmentation because it helps reduce excess melanin production by inhibiting tyrosinase, the enzyme responsible for skin pigmentation

For a substance or method to be included on the WADA Prohibited List, the substance or method must meet any two of the following three criteria: 1) It has the potential to enhance or enhances sport performance 2) It represents and actual or potential health risk to the athlete 3) It violates the spirit of sport Harmful Effects Although the effects of IGF-1 are well examined, the distribution and utilization for its proper medical use in humans in the pharmaceutical market is extremely limited

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