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These unique traits are unlike all of the synthetic hypnotic medications that tend to alter normal sleeping patterns dramatically

10.1016/j.trci.2018.03.009 51 DadarM.ShahaliY.ChakrabortyS.PrasadM.TahooriF.TiwariR.et al (2019)

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The cardiovascular safety of TRESIBA was evaluated in one double blinded, event driven trial of 2 year median duration in patients with type 2 diabetes at high risk of cardiovascular events [see Clinical Studies ]

Additionally, the exposed group demonstrated significantly higher PLA 2 and SMase enzyme activity, with their median values being 518 and 706 AFU/mg, compared to 267 and 444 AFU/mg in the unexposed workers

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